The Islamic Revolution of Iran under the leadership of Imam Khomeini (RA) entered into a full-fledged and strategic challenge with rival organizations and parties due to following the principles and foundations of the Shiite and Ahl al-Bayt (AS) schools. One of these organizations is the People's Mojahedin Organization (MKO) with eclectic principles and foundations, which was established in the 1340s by three members of the student branch of the 'Freedom Movement'. From the very beginning, this organization claimed to save Iran from the yoke of American imperialism and its internal allies (the Pahlavi regime) by resorting to armed struggle. This terrorist organization has been an enemy of the Islamic revolution and principle of velayet- faqih for five decades despite all the ups and downs of its activities. The long-standing conflict between the Mojahedin Khalq Organization (MKO) and the Islamic Revolution led by Imam Khomeini is in the religious, political, social and cultural fields. In the field of belief, non-belief in the universality of the principles and foundations of Islam and eclecticism with Marxist principles and foundations and 'confiscation of the desirable' Islamic concepts and values in order to cover and camouflage Marxist infidelity and atheism. In the political sphere, dependence on foreign and imported Marxist models. In the cultural and social context, disbelief in the real role of the masses in the process of revolutionary change.